Neural tissue, comprised of nerve fibers and the structures immediately surrounding them, is closely connected to muscles, lymph vessels and fascial structures. Under normal conditions neural tissue can move freely between muscles, bones and connective tissue such as fascial tissue layers.
Normal movement of nerve tissue may become obstructed from restricted joint mobility or muscle tightness, which can cause radiating pain. If a nerve is constantly compressed or stretched, the transportation of nutrients inside is restricted. This causes increased secretion of inflammation mediators.